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Inhibition of Disruptor of Telomeric Silencing 1-Like Alleviated Renal Ischemia and Reperfusion Injury-Induced Fibrosis by Blocking PI3K/AKT-Mediated Oxidative Stress

BACKGROUND: Ischemia/reperfusion (I/R) injury is a major cause of acute kidney injury, usually occurs during renal surgeries, and may eventually lead to chronic kidney diseases. However, effective therapeutic targets for renal I/R injury remain limited. PURPOSE: In the present study, we investigated...

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Bibliografische gegevens
Gepubliceerd in:Drug Des Devel Ther
Hoofdauteurs: Yang, Chuan, Chen, Zhiyuan, Yu, Hua, Liu, Xiuheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939406/
https://ncbi.nlm.nih.gov/pubmed/31920287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S224909
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