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Mapping and editing animal mitochondrial genomes: can we overcome the challenges?
The animal mitochondrial genome, although small, can have a big impact on health and disease. Non-pathogenic sequence variation among mitochondrial DNA (mtDNA) haplotypes influences traits including fertility, healthspan and lifespan, whereas pathogenic mutations are linked to incurable mitochondria...
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| Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6939374/ https://ncbi.nlm.nih.gov/pubmed/31787046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2019.0187 |
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