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Targeting the Programmed Axon Degeneration Pathway as a Potential Therapeutic for Charcot-Marie-Tooth Disease
The programmed axon degeneration pathway has emerged as an important process contributing to the pathogenesis of several neurological diseases. The most crucial events in this pathway include activation of the central executioner SARM1 and NAD(+) depletion, which leads to an energetic failure and ul...
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| Publicado en: | Brain Res |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6939145/ https://ncbi.nlm.nih.gov/pubmed/31689415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.146539 |
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