A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy

Mitochondrial dysfunction is the determinant insult of ischemia-reperfusion injury. Autologous mitochondrial transplantation involves supplying one’s healthy mitochondria to the ischemic region harboring damaged mitochondria. The authors used in vivo swine to show that mitochondrial transplantation...

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Enregistré dans:
Détails bibliographiques
Publié dans:JACC Basic Transl Sci
Auteurs principaux: Shin, Borami, Saeed, Mossab Y., Esch, Jesse J., Guariento, Alvise, Blitzer, David, Moskowitzova, Kamila, Ramirez-Barbieri, Giovanna, Orfany, Arzoo, Thedsanamoorthy, Jerusha K., Cowan, Douglas B., Inkster, James A., Snay, Erin R., Staffa, Steven J., Packard, Alan B., Zurakowski, David, del Nido, Pedro J., McCully, James D.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
PRECLINICAL RESEARCH
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938990/
https://ncbi.nlm.nih.gov/pubmed/31909298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.08.007
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