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Sequential ALK inhibitor treatment benefits patient with leptomeningeal metastasis harboring non‐EML4‐ALK rearrangements detected from cerebrospinal fluid: A case report

A 47‐year‐old female with ALK‐rearranged lung adenocarcinoma developed leptomeningeal metastasis (LM) after progression on first‐line crizotinib. Alectinib 300 mg was commenced and the patient achieved clinical and radiographic improvements. After nine months of alectinib 300 mg, she started to expe...

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Dettagli Bibliografici
Pubblicato in:Thorac Cancer
Autori principali: Li, Zhaona, Li, Pupu, Yan, Bing, Gao, Qiongqiong, Jiang, Xiangli, Zhan, Zhongli, Yan, Qingna, Lizaso, Analyn, Huang, Chun
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons Australia, Ltd 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938764/
https://ncbi.nlm.nih.gov/pubmed/31766077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13259
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