Regulation of Insulin-Like Growth Factor 2 by Oocyte-Secreted Factors in Primary Human Granulosa Cells

CONTEXT: Human granulosa cells (hGCs) produce and respond to insulin-like growth factor 2 (IGF2) but whether the oocyte participates in IGF2 regulation in humans is unknown. OBJECTIVE: To determine the role of oocyte-secreted factors (OSFs) such as growth differentiation factor 9 (GDF9) and bone mor...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Hobeika, Elie, Armouti, Marah, Fierro, Michele A, Winston, Nichola, Scoccia, Humberto, Zamah, Alberuni M, Stocco, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938692/
https://ncbi.nlm.nih.gov/pubmed/31588501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz057
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