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ForestQC: Quality control on genetic variants from next-generation sequencing data using random forest

Next-generation sequencing technology (NGS) enables the discovery of nearly all genetic variants present in a genome. A subset of these variants, however, may have poor sequencing quality due to limitations in NGS or variant callers. In genetic studies that analyze a large number of sequenced indivi...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Li, Jiajin, Jew, Brandon, Zhan, Lingyu, Hwang, Sungoo, Coppola, Giovanni, Freimer, Nelson B., Sul, Jae Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938691/
https://ncbi.nlm.nih.gov/pubmed/31851693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007556
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