Adaptive protein translation by the integrated stress response maintains the proliferative and migratory capacity of lung adenocarcinoma cells

The integrated stress response (ISR) is a conserved pathway which is activated by cells that are exposed to stress. In lung adenocarcinoma (LUAD), activation of the ATF4 branch of the ISR by certain oncogenic mutations has been linked to the regulation of amino acid metabolism. In the present study,...

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Publicado no:Mol Cancer Res
Main Authors: Albert, Alexandra E., Adua, Sally J., Cai, Wesley L., Arnal-Estapé, Anna, Cline, Gary W., Liu, Zongzhi, Zhao, Minghui, Cao, Paul D., Mariappan, Malaiyalam, Nguyen, Don X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938689/
https://ncbi.nlm.nih.gov/pubmed/31551255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0245
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