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GLIS3 binds pancreatic beta cell regulatory regions alongside other islet transcription factors
The Krüppel-like zinc finger transcription factor Gli-similar 3 (GLIS3) plays a critical role in the regulation of pancreatic beta cells, with global Glis3 knockout mice suffering from severe hyperglycemia and dying by post-natal day 11. In addition, GLIS3 has been shown to directly regulate the ear...
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| Udgivet i: | J Endocrinol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6938561/ https://ncbi.nlm.nih.gov/pubmed/31340201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-19-0182 |
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