Rapid, efficient, and economical synthesis of PET tracers in a droplet microreactor: application to O-(2-[(18)F]fluoroethyl)-L-tyrosine ([(18)F]FET)

BACKGROUND: Conventional scale production of small batches of PET tracers (e.g. for preclinical imaging) is an inefficient use of resources. Using O-(2-[(18)F]fluoroethyl)-L-tyrosine ([(18)F]FET), we demonstrate that simple microvolume radiosynthesis techniques can improve the efficiency of producti...

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Bibliographic Details
Published in:EJNMMI Radiopharm Chem
Main Authors: Lisova, Ksenia, Chen, Bao Ying, Wang, Jia, Fong, Kelly Mun-Ming, Clark, Peter M., van Dam, R. Michael
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938530/
https://ncbi.nlm.nih.gov/pubmed/31893318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-019-0082-3
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