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Hypofibrinolysis induced by tranexamic acid does not influence inflammation and mortality in a polymicrobial sepsis model

The biological relevance of fibrinolysis to the host response to sepsis is illustrated by pathogens such as S. pyogenes and Y. pestis, whose virulence factors are proteins that challenge the balance between pro- and anti-fibrinolytic factors of the host, and by the consistent finding of hypofibrinol...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Campos Nogueira, Yzabella Alves, Gomes da Costa, Loredana Nilkenes, Levy, Carlos Emilio, Orsi, Fernanda Andrade, de Lima, Franciele, Annichinno-Bizzacchi, Joyce M., De Paula, Erich Vinicius
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938370/
https://ncbi.nlm.nih.gov/pubmed/31891611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226871
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