Pharmacodynamic Analysis of Daptomycin-treated Enterococcal Bacteremia: It Is Time to Change the Breakpoint

BACKGROUND: Currently, there is debate over whether the daptomycin susceptibility breakpoint for enterococci (ie, minimum inhibitory concentration [MIC] ≤4 mg/L) is appropriate. In bacteremia, observational data support prescription of high doses (>8 mg/kg). However, pharmacodynamic targets assoc...

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Enregistré dans:
Détails bibliographiques
Publié dans:Clin Infect Dis
Auteurs principaux: Avery, Lindsay M, Kuti, Joseph L, Weisser, Maja, Egli, Adrian, Rybak, Michael J, Zasowski, Evan J, Arias, Cesar A, Contreras, German A, Chong, Pearlie P, Aitken, Samuel L, DiPippo, Adam J, Wang, Jann-Tay, Britt, Nicholas S, Nicolau, David P
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Articles and Commentaries
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938208/
https://ncbi.nlm.nih.gov/pubmed/30188976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy749
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