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High CO(2) Downregulates Skeletal Muscle Protein Anabolism via AMP-activated Protein Kinase α2–mediated Depressed Ribosomal Biogenesis
High CO(2) retention, or hypercapnia, is associated with worse outcomes in patients with chronic pulmonary diseases. Skeletal muscle wasting is also an independent predictor of poor outcomes in patients with acute and chronic pulmonary diseases. Although previous evidence indicates that high CO(2) a...
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| Udgivet i: | Am J Respir Cell Mol Biol |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Thoracic Society
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6938128/ https://ncbi.nlm.nih.gov/pubmed/31264907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0061OC |
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