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Synthesis, molecular docking, and antiepileptic activity of novel phthalimide derivatives bearing amino acid conjugated anilines

A series of N-aryl-2-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanamides derivatives were synthesized in two steps. Phthalic anhydride and phenylalanine are first reacted under microwave radiation to form 2-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanoic acid, which finally took part in an amidation reacti...

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Detalhes bibliográficos
Publicado no:Res Pharm Sci
Main Authors: Asadollahi, Azar, Asadi, Mehdi, Hosseini, Faezeh Sadat, Ekhtiari, Zeinab, Biglar, Mahmood, Amanlou, Massoud
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937752/
https://ncbi.nlm.nih.gov/pubmed/32038733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.272562
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