Antigen-driven selection of antibodies against SSA, SSB and the centromere ‘complex’, including a novel antigen, MIS12 complex, in human salivary glands

OBJECTIVES: Recent evidences have revealed that anti-SSA/SSB antibodies, the major autoantibodies in Sjögren's syndrome (SS), are produced in salivary glands. This study aims to clarify overall of autoantibody production at lesion site, including anti-centromere antibody (ACA)-positive SS. METH...

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Dades bibliogràfiques
Publicat a:Ann Rheum Dis
Autors principals: Takeshita, Masaru, Suzuki, Katsuya, Kaneda, Yukari, Yamane, Humitsugu, Ikeura, Kazuhiro, Sato, Hidekazu, Kato, Shin, Tsunoda, Kazuyuki, Arase, Hisashi, Takeuchi, Tsutomu
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2020
Matèries:
Sjögren's Syndrome
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937410/
https://ncbi.nlm.nih.gov/pubmed/31611218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2019-215862
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