Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population

OBJECTIVE: The causality and pathogenic mechanism of microbiome composition remain elusive in many diseases, including autoimmune diseases such as rheumatoid arthritis (RA). This study aimed to elucidate gut microbiome’s role in RA pathology by a comprehensive metagenome-wide association study (MWAS...

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Pubblicato in:Ann Rheum Dis
Autori principali: Kishikawa, Toshihiro, Maeda, Yuichi, Nii, Takuro, Motooka, Daisuke, Matsumoto, Yuki, Matsushita, Masato, Matsuoka, Hidetoshi, Yoshimura, Maiko, Kawada, Shoji, Teshigawara, Satoru, Oguro, Eri, Okita, Yasutaka, Kawamoto, Keisuke, Higa, Shinji, Hirano, Toru, Narazaki, Masashi, Ogata, Atsushi, Saeki, Yukihiko, Nakamura, Shota, Inohara, Hidenori, Kumanogoh, Atsushi, Takeda, Kiyoshi, Okada, Yukinori
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2020
Soggetti:
Rheumatoid Arthritis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937407/
https://ncbi.nlm.nih.gov/pubmed/31699813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2019-215743
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