Feasibility study of using high-throughput drug sensitivity testing to target recurrent glioblastoma stem cells for individualized treatment

BACKGROUND: Despite the well described heterogeneity in glioblastoma (GBM), treatment is standardized, and clinical trials investigate treatment effects at population level. Genomics-driven oncology for stratified treatments allow clinical decision making in only a small minority of screened patient...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Skaga, Erlend, Kulesskiy, Evgeny, Brynjulvsen, Marit, Sandberg, Cecilie J., Potdar, Swapnil, Langmoen, Iver A., Laakso, Aki, Gaál-Paavola, Emília, Perola, Markus, Wennerberg, Krister, Vik-Mo, Einar O.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937360/
https://ncbi.nlm.nih.gov/pubmed/31889236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-019-0253-6
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