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Using transfer learning from prior reference knowledge to improve the clustering of single-cell RNA-Seq data

In many research areas scientists are interested in clustering objects within small datasets while making use of prior knowledge from large reference datasets. We propose a method to apply the machine learning concept of transfer learning to unsupervised clustering problems and show its effectivenes...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Mieth, Bettina, Hockley, James R. F., Görnitz, Nico, Vidovic, Marina M.-C., Müller, Klaus-Robert, Gutteridge, Alex, Ziemek, Daniel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937257/
https://ncbi.nlm.nih.gov/pubmed/31889137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56911-z
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