Immunotherapy using anti-PD-1 and anti-PD-L1 in Leishmania amazonensis-infected BALB/c mice reduce parasite load

Leishmaniasis is a neglected disease, for which current treatment presents numerous issues. Leishmania amazonensis is the etiological agent of cutaneous and diffuse cutaneous leishmaniasis. The roles of the programmed death-1 (PD-1) receptor on lymphocytes and its ligand (PD-L1) on antigen-presentin...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: da Fonseca-Martins, Alessandra M., Ramos, Tadeu D., Pratti, Juliana E. S., Firmino-Cruz, Luan, Gomes, Daniel Claudio Oliveira, Soong, Lynn, Saraiva, Elvira M., de Matos Guedes, Herbert L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937231/
https://ncbi.nlm.nih.gov/pubmed/31889072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56336-8
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