Oligomeric Aβ in the monkey brain impacts synaptic integrity and induces accelerated cortical aging

As the average age of the population continues to rise, the number of individuals affected with age-related cognitive decline and Alzheimer’s disease (AD) has increased and is projected to cost more than $290 billion in the United States in 2019. Despite significant investment in research over the l...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Beckman, Danielle, Ott, Sean, Donis-Cox, Kristine, Janssen, William G., Bliss-Moreau, Eliza, Rudebeck, Peter H., Baxter, Mark G., Morrison, John H.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2019
Assuntos:
Arthur M. Sackler Colloquium Using Monkey Models to Understand and Develop Treatments for Human Brain Disorders
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936351/
https://ncbi.nlm.nih.gov/pubmed/31871145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902301116
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