Lentivirus-mediated downregulation of α-synuclein reduces neuroinflammation and promotes functional recovery in rats with spinal cord injury

BACKGROUND: The prognosis of spinal cord injury (SCI) is closely related to secondary injury, which is dominated by neuroinflammation. There is evidence that α-synuclein aggregates after SCI and that inhibition of α-synuclein aggregation can improve the survival of neurons after SCI, but the mechani...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Zeng, Hong, Liu, Nan, Yang, Yan-yan, Xing, Hua-yi, Liu, Xiao-xie, Li, Fang, La, Gao-yan, Huang, Meng-jie, Zhou, Mou-wang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936070/
https://ncbi.nlm.nih.gov/pubmed/31888724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1658-2
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