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Region-based interaction detection in genome-wide case-control studies

BACKGROUND: In genome-wide association study (GWAS), conventional interaction detection methods such as BOOST are mostly based on SNP-SNP interactions. Although single nucleotides are the building blocks of human genome, single nucleotide polymorphisms (SNPs) are not necessarily the smallest functio...

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Bibliografiske detaljer
Udgivet i:BMC Med Genomics
Main Authors: Zhang, Sen, Jiang, Wei, Ma, Ronald CW, Yu, Weichuan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936067/
https://ncbi.nlm.nih.gov/pubmed/31888606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0583-7
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