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MECoRank: cancer driver genes discovery simultaneously evaluating the impact of SNVs and differential expression on transcriptional networks

BACKGROUND: Although there are huge volumes of genomic data, how to decipher them and identify driver events is still a challenge. The current methods based on network typically use the relationship between genomic events and consequent changes in gene expression to nominate putative driver genes. B...

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Podrobná bibliografie
Vydáno v:BMC Med Genomics
Hlavní autoři: Hui, Ying, Wei, Pi-Jing, Xia, Junfeng, Wang, Yu-Tian, Zheng, Chun-Hou
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936061/
https://ncbi.nlm.nih.gov/pubmed/31888623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0582-8
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