Zika Virus Nonstructural Protein 1 Disrupts Glycosaminoglycans and Causes Permeability in Developing Human Placentas

BACKGROUND: During pregnancy, the Zika flavivirus (ZIKV) infects human placentas, inducing defects in the developing fetus. The flavivirus nonstructural protein 1 (NS1) alters glycosaminoglycans on the endothelium, causing hyperpermeability in vitro and vascular leakage in vivo in a tissue-dependent...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Infect Dis
Päätekijät: Puerta-Guardo, Henry, Tabata, Takako, Petitt, Matthew, Dimitrova, Milena, Glasner, Dustin R, Pereira, Lenore, Harris, Eva
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Major Articles and Brief Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936002/
https://ncbi.nlm.nih.gov/pubmed/31250000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz331
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