Lysosome-associated membrane protein-2 deficiency increases the risk of reactive oxygen species-induced ferroptosis in retinal pigment epithelial cells

Lysosome-associated membrane protein-2 (LAMP2), is a highly glycosylated lysosomal membrane protein involved in chaperone mediated autophagy. Mutations of LAMP2 cause the classic triad of myopathy, cardiomyopathy and encephalopathy of Danon disease (DD). Additionally, retinopathy has also been obser...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Lee, Jong-Jer, Ishihara, Kenji, Notomi, Shoji, Efstathiou, Nikolaos E., Ueta, Takashi, Maidana, Daniel, Chen, Xiaohong, Iesato, Yasuhiro, Caligiana, Alberto, Vavvas, Demetrios G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935401/
https://ncbi.nlm.nih.gov/pubmed/31672277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.10.138
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