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Abatacept in Early Diffuse Cutaneous Systemic Sclerosis – Results of a Phase 2 Investigator-Initiated, Multicenter, Double-Blind Randomized Placebo-Controlled Trial

OBJECTIVES: T cells play a key role in the pathogenesis of early systemic sclerosis. This study assessed the safety and efficacy of abatacept in patients with diffuse cutaneous systemic sclerosis (dcSSc). METHODS: A 12-month, randomized, double-blind, placebo-controlled trial with participants rando...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Arthritis Rheumatol
Main Authors: Khanna, Dinesh, Spino, Cathie, Johnson, Sindhu, Chung, Lorinda, Whitfield, Michael, Denton, Christopher P., Berrocal, Veronica, Jennifer, Franks, Mehta, Bhaven, Molitor, Jerry, Steen, Virginia D., Lafyatis, Robert, Simms, Robert W., Gill, Anna, Kafaja, Suzanne, Frech, Tracy M., Hsu, Vivien, Domsic, Robyn T., Pope, Janet E., Gordon, Jessica K., Mayes, Maureen D., Schiopu, Elena, Young, Amber, Sandorfi, Nora, Park, Jane, Hant, Faye N., Bernstein, Elana J., Chatterjee, Soumya, Castelino, Flavia V., Ajam, Ali, Wang, Yue, Wood, Tammara, Allanore, Yannick, Matucci-Cerinic, Marco, Distler, Oliver, Singer, Ora, Bush, Erica, Fox, David, Furst, Daniel E.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935399/
https://ncbi.nlm.nih.gov/pubmed/31342624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41055
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