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Computational and Experimental Study of Inhibitors Design for Aldolase A
Glycolytic enzyme fructose-bisphosphate aldolase A is an emerging therapeutic target in cancer. Recently we have solved the crystal structure of murine aldolase in complex with naphthalene-2,6-diyl bisphosphate (ND1) that served as a template of the design of bisphosphate-based inhibitors. In this w...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Phys Chem B |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6935369/ https://ncbi.nlm.nih.gov/pubmed/31268712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b04551 |
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