A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage

The classical model of tissue renewal posits that small numbers of quiescent stem cells (SCs) give rise to proliferating transit-amplifying cells before terminal differentiation. However, many organs house pools of SCs with proliferative and differentiation potentials that diverge from this template...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Sharir, Amnon, Marangoni, Pauline, Zilionis, Rapolas, Wan, Mian, Wald, Tomas, Hu, Jimmy K., Kawaguchi, Kyogo, Castillo-Azofeifa, David, Epstein, Leo, Harrington, Kyle, Pagella, Pierfrancesco, Mitsiadis, Thimios, Siebel, Christian W., Klein, Allon M., Klein, Ophir D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935352/
https://ncbi.nlm.nih.gov/pubmed/31481792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0378-2
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