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BAP31 regulates IRAK1-dependent neuroinflammation in microglia

BACKGROUND: Microglia, the mononuclear immune cells of the central nervous system (CNS), are essential for the maintenance of CNS homeostasis. BAP31, a resident and ubiquitously expressed protein of the endoplasmic reticulum, serves as a sorting factor for its client proteins, mediating the subseque...

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Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Liu, Xia, Jiao, Kun, Jia, Cong-cong, Li, Guo-xun, Yuan, Qing, Xu, Ji-kai, Hou, Yue, Wang, Bing
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935200/
https://ncbi.nlm.nih.gov/pubmed/31883536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1661-7
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