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Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation

BACKGROUND: Renal endothelial cells from glomerular, cortical, and medullary kidney compartments are exposed to different microenvironmental conditions and support specific kidney processes. However, the heterogeneous phenotypes of these cells remain incompletely inventoried. Osmotic homeostasis is...

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Bibliografische gegevens
Gepubliceerd in:J Am Soc Nephrol
Hoofdauteurs: Dumas, Sébastien J., Meta, Elda, Borri, Mila, Goveia, Jermaine, Rohlenova, Katerina, Conchinha, Nadine V., Falkenberg, Kim, Teuwen, Laure-Anne, de Rooij, Laura, Kalucka, Joanna, Chen, Rongyuan, Khan, Shawez, Taverna, Federico, Lu, Weisi, Parys, Magdalena, De Legher, Carla, Vinckier, Stefan, Karakach, Tobias K., Schoonjans, Luc, Lin, Lin, Bolund, Lars, Dewerchin, Mieke, Eelen, Guy, Rabelink, Ton J., Li, Xuri, Luo, Yonglun, Carmeliet, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935008/
https://ncbi.nlm.nih.gov/pubmed/31818909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019080832
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