A Randomized Trial Comparing the Safety, Adherence, and Pharmacodynamics Profiles of Two Doses of Sodium Bicarbonate in CKD: the BASE Pilot Trial

BACKGROUND: Oral sodium bicarbonate (NaHCO(3)) may preserve kidney function in CKD, even if initiated when serum bicarbonate concentration is normal. Adequately powered trials testing this hypothesis have not been conducted, partly because the best dose for testing is unknown. METHODS: This multicen...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Am Soc Nephrol
Κύριοι συγγραφείς: Raphael, Kalani L., Isakova, Tamara, Ix, Joachim H., Raj, Dominic S., Wolf, Myles, Fried, Linda F., Gassman, Jennifer J., Kendrick, Cynthia, Larive, Brett, Flessner, Michael F., Mendley, Susan R., Hostetter, Thomas H., Block, Geoffrey A., Li, Ping, Middleton, John P., Sprague, Stuart M., Wesson, Donald E., Cheung, Alfred K.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Nephrology 2020
Θέματα:
Clinical Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934992/
https://ncbi.nlm.nih.gov/pubmed/31848294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019030287
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