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Efficient Synthesis of Norbuprenorphines Coupled with Enkephalins and Investigation of Their Permeability

An efficient approach for the synthesis of norbuprenorphin derivatives through coupling of enkephalins and norbuprenorphine intermediates is described. Norbuprenorphine derivative was synthesized from thebaine and then, its reaction with succinic acid and phthalic acid was also studied. Meanwhile, t...

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Publicat a:Iran J Pharm Res
Autors principals: Balalaie, Saeed, Malakoutikhah, Morteza, Teixidó, Meritxell, Fathi Vavsari, Vaezeh, Giralt, Ernest, Haghighatnia, Yaghoub, Hamdan, Fatima, Arabanian, Armin
Format: Artigo
Idioma:Inglês
Publicat: Shaheed Beheshti University of Medical Sciences 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934973/
https://ncbi.nlm.nih.gov/pubmed/32641938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.14712.12602
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