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Distinct role of Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) in inhibiting cargo-loading and release of extracellular vesicles

Exosomes, vehicles for intercellular communication, are formed intracellularly within multivesicular bodies (MVBs) and are released upon fusion with the plasma membrane. For their biogenesis, proper cargo loading to exosomes and vesicle traffic for extracellular release are required. Previously we s...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Lee, Byung Rho, Sanstrum, Bethany J., Liu, Yutao, Kwon, Sang-Ho
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934595/
https://ncbi.nlm.nih.gov/pubmed/31882861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56635-0
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