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Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas

Glioma is recognized to be a highly heterogeneous CNS malignancy, whose diverse cellular composition and cellular interactions have not been well characterized. To gain new clinical- and biological-insights into the genetically-bifurcated IDH1 mutant (mt) vs wildtype (wt) forms of glioma, we integra...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Berens, Michael E., Sood, Anup, Barnholtz-Sloan, Jill S., Graf, John F., Cho, Sanghee, Kim, Seungchan, Kiefer, Jeffrey, Byron, Sara A., Halperin, Rebecca F., Nasser, Sara, Adkins, Jonathan, Cuyugan, Lori, Devine, Karen, Ostrom, Quinn, Couce, Marta, Wolansky, Leo, McDonough, Elizabeth, Schyberg, Shannon, Dinn, Sean, Sloan, Andrew E., Prados, Michael, Phillips, Joanna J., Nelson, Sarah J., Liang, Winnie S., Al-Kofahi, Yousef, Rusu, Mirabela, Zavodszky, Maria I., Ginty, Fiona
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934292/
https://ncbi.nlm.nih.gov/pubmed/31881020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219724
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