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Structural and Functional Modularity of the U2 snRNP in pre-mRNA Splicing
The U2 small nuclear ribonucleoprotein (snRNP) is an essential component of the spliceosome, the cellular machine responsible for removing introns from precursor mRNAs (pre-mRNAs) in all eukaryotes. U2 is an extraordinarily dynamic splicing factor and the most frequently mutated in cancers. Cryo-ele...
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| Udgivet i: | Crit Rev Biochem Mol Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6934263/ https://ncbi.nlm.nih.gov/pubmed/31744343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2019.1691497 |
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