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SSBP1 faux pas in mitonuclear tango causes optic neuropathy

Mitochondrial dysfunction or loss is evident in neurodegenerative diseases. Furthermore, mitochondrial DNA (mtDNA) mutations associated with NADH dehydrogenase subunits and nuclear gene mutations that affect mitochondrial function result in optic neuropathies. In this issue of the JCI, Del Dotto et...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Zelinger, Lina, Swaroop, Anand
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934202/
https://ncbi.nlm.nih.gov/pubmed/31738184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132532
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