A harlequin ichthyosis pig model with a novel ABCA12 mutation can be rescued by acitretin treatment

Harlequin ichthyosis (HI) is a severe genetic skin disorder and caused by mutation in the ATP-binding cassette A12 (ABCA12) gene. The retinoid administration has dramatically improved long-term survival of HI, but improvements are still needed. However, the ABCA12 null mice failed to respond to reti...

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Publicado en:J Mol Cell Biol
Autores principales: Wang, Xiao, Cao, Chunwei, Li, Yongshun, Hai, Tang, Jia, Qitao, Zhang, Ying, Zheng, Qiantao, Yao, Jing, Qin, Guosong, Zhang, Hongyong, Song, Ruigao, Wang, Yanfang, Shui, Guanghou, Lam, Sin Man, Liu, Zhonghua, Wei, Hong, Meng, Anming, Zhou, Qi, Zhao, Jianguo
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934153/
https://ncbi.nlm.nih.gov/pubmed/30925591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz021
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