Structural Insights Into TDP-43 and Effects of Post-translational Modifications

Transactive response DNA binding protein (TDP-43) is a key player in neurodegenerative diseases. In this review, we have gathered and presented structural information on the different regions of TDP-43 with high resolution structures available. A thorough understanding of TDP-43 structure, effect of...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: François-Moutal, Liberty, Perez-Miller, Samantha, Scott, David D., Miranda, Victor G., Mollasalehi, Niloufar, Khanna, May
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934062/
https://ncbi.nlm.nih.gov/pubmed/31920533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00301
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