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Identifying Clusters of High Confidence Homologies in Multiple Sequence Alignments

Multiple sequence alignment (MSA) is ubiquitous in evolution and bioinformatics. MSAs are usually taken to be a known and fixed quantity on which to perform downstream analysis despite extensive evidence that MSA accuracy and uncertainty affect results. These errors are known to cause a wide range o...

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Publicat a:Mol Biol Evol
Autors principals: Ali, Raja Hashim, Bogusz, Marcin, Whelan, Simon
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933875/
https://ncbi.nlm.nih.gov/pubmed/31209473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz142
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