New (99m)Tc-Labeled Digitoxigenin Derivative for Cancer Cell Identification

[Image: see text] In recent years, cardiac glycosides (CGs) have been investigated as potential antiviral and anticancer drugs. Digitoxigenin (DIG) and other CGs have been shown to bind and inhibit Na(+)/K(+)-adenosinetriphosphatase (ATPase). Tumor cells show a higher expression rate of the Na(+)/K(...

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Veröffentlicht in:ACS Omega
Hauptverfasser: Munkert, Jennifer, Gomes, Eliza R., Marostica, Lucas L., Cota, Betânia B., Lopes, Cristina L. M., Andrade, Saulo F., Filho, José D. de Souza, Alves, Ricardo J., Oliveira, Monica C., Braga, Fernão C., Simões, Cláudia M. O., Pádua, Rodrigo M., de Barros, André L. B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2019
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933791/
https://ncbi.nlm.nih.gov/pubmed/31891085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03167
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