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New (99m)Tc-Labeled Digitoxigenin Derivative for Cancer Cell Identification

[Image: see text] In recent years, cardiac glycosides (CGs) have been investigated as potential antiviral and anticancer drugs. Digitoxigenin (DIG) and other CGs have been shown to bind and inhibit Na(+)/K(+)-adenosinetriphosphatase (ATPase). Tumor cells show a higher expression rate of the Na(+)/K(...

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Bibliografski detalji
Izdano u:ACS Omega
Glavni autori: Munkert, Jennifer, Gomes, Eliza R., Marostica, Lucas L., Cota, Betânia B., Lopes, Cristina L. M., Andrade, Saulo F., Filho, José D. de Souza, Alves, Ricardo J., Oliveira, Monica C., Braga, Fernão C., Simões, Cláudia M. O., Pádua, Rodrigo M., de Barros, André L. B.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2019
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933791/
https://ncbi.nlm.nih.gov/pubmed/31891085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03167
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