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CD8(+) T cells exhaustion induced by myeloid‐derived suppressor cells in myelodysplastic syndromes patients might be through TIM3/Gal‐9 pathway

CD8(+) T cells play a central role in antitumour immunity, which often exhibit ‘exhaustion’ in the setting of malignancy and chronic viral infection due to T cell immunoglobulin and mucin domain 3 (TIM3) and myeloid‐derived suppressor cells (MDSCs). Our team previously found that overactive MDSCs an...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Tao, Jinglian, Han, Dong, Gao, Shan, Zhang, Wei, Yu, Hong, Liu, Pei, Fu, Rong, Li, Lijuan, Shao, Zonghong
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933355/
https://ncbi.nlm.nih.gov/pubmed/31756785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14825
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