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Manganese activates autophagy to alleviate endoplasmic reticulum stress–induced apoptosis via PERK pathway

Overexposure to manganese (Mn) is neurotoxic. Our previous research has demonstrated that the interaction of endoplasmic reticulum (ER) stress and autophagy participates in the early stage of Mn‐mediated neurotoxicity in mouse. However, the mechanisms of ER stress signalling pathways in the initiati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Liu, Chang, Yan, Dong‐Ying, Wang, Can, Ma, Zhuo, Deng, Yu, Liu, Wei, Xu, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933331/
https://ncbi.nlm.nih.gov/pubmed/31639278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14732
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