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p53‐dependent transcriptional suppression of BAG3 protects cells against metabolic stress via facilitation of p53 accumulation

Solid tumour frequently undergoes metabolic stress during tumour development because of inadequate blood supply and the high nutrient expenditure. p53 is activated by glucose limitation and maintains cell survival via triggering metabolic checkpoint. However, the exact downstream contributors are no...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Wang, Jia‐Mei, Liu, Bao‐Qin, Du, Zhen‐Xian, Li, Chao, Sun, Jia, Yan, Jing, Jiang, Jing‐Yi, Wang, Hua‐Qin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933324/
https://ncbi.nlm.nih.gov/pubmed/31657880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14764
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