Insulin-induced hypoglycemia suppresses pulsatile LH secretion and arcuate Kiss1 cell activation in female mice.

Stress suppresses pulsatile LH secretion in a variety of species, however the mechanism underlying this inhibition of reproductive function remains unclear. Metabolic stress, particularly hypoglycemia, is a clinically-relevant stress type that is modeled with bolus insulin injection (insulin-induced...

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Publicado en:J Neuroendocrinol
Autores principales: McCosh, Richard B., Kreisman, Michael J., Tian, Katherine, Ho, Bryan S., Thackray, Varykina G., Breen, Kellie M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933080/
https://ncbi.nlm.nih.gov/pubmed/31758872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jne.12813
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