Treatment With 2-BFI Attenuated Spinal Cord Injury by Inhibiting Oxidative Stress and Neuronal Apoptosis via the Nrf2 Signaling Pathway

Previous reports showed that 2-(-2-benzofuranyl)-2-imidazoline (2-BFI) has antioxidant, anti-inflammatory and anti-apoptotic effects on neuroprotection in numerous disorders. However, the precise mechanisms remain elusive. The nuclear factor c factor 2 (Nrf2)/antioxidant response element (ARE) signa...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Lin, Xiaolong, Zhu, Jie, Ni, Haibo, Rui, Qin, Sha, Weiping, Yang, Huilin, Li, Di, Chen, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932985/
https://ncbi.nlm.nih.gov/pubmed/31920564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00567
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