Absence of a synergic nigral proapoptotic effect triggered by REM sleep deprivation in the rotenone model of Parkinson´s disease

Excitotoxicity has been related to play a crucial role in Parkinson's disease (PD) pathogenesis. Pedunculopontine tegmental nucleus (PPT) represents one of the major sources of glutamatergic afferences to nigrostriatal pathway and putative reciprocal connectivity between these structures may ex...

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Dettagli Bibliografici
Pubblicato in:Sleep Sci
Autori principali: Kmita, Luana C, Ilkiw, Jessica L, Rodrigues, Lais S, Targa, Adriano DS, Noseda, Ana Carolina D, dos-Santos, Patrícia, Fagotti, Juliane, Trindade, Edvaldo S., Lima, Marcelo MS
Natura: Artigo
Lingua:Inglês
Pubblicazione: Brazilian Association of Sleep and Latin American Federation of Sleep 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932851/
https://ncbi.nlm.nih.gov/pubmed/31890096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5935/1984-0063.20190078
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