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Classification of drug‐induced hERG potassium‐channel block from electrocardiographic T‐wave features using artificial neural networks

BACKGROUND: Human ether‐à‐go‐go‐related gene (hERG) potassium‐channel block represents a harmful side effect of drug therapy that may cause torsade de pointes (TdP). Analysis of ventricular repolarization through electrocardiographic T‐wave features represents a noninvasive way to accurately evaluat...

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Bibliographic Details
Published in:Ann Noninvasive Electrocardiol
Main Authors: Morettini, Micaela, Peroni, Chiara, Sbrollini, Agnese, Marcantoni, Ilaria, Burattini, Laura
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931415/
https://ncbi.nlm.nih.gov/pubmed/31347753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/anec.12679
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