Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD

BACKGROUND: Hedgehog (HH) pathway is constantly under scrutiny in the context of organ development. Lung morphogenesis requires HH signalling which participates thereafter to the pulmonary homeostasis by regulating epithelial cell quiescence and repair. Since epithelial remodelling is a hallmark of...

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Библиографические подробности
Опубликовано в: :EBioMedicine
Главные авторы: Belgacemi, Randa, Luczka, Emilie, Ancel, Julien, Diabasana, Zania, Perotin, Jeanne-Marie, Germain, Adeline, Lalun, Nathalie, Birembaut, Philippe, Dubernard, Xavier, Mérol, Jean-Claude, Delepine, Gonzague, Polette, Myriam, Deslée, Gaëtan, Dormoy, Valérian
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
Предметы:
Research paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931110/
https://ncbi.nlm.nih.gov/pubmed/31877414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.11.033
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