Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD

BACKGROUND: Hedgehog (HH) pathway is constantly under scrutiny in the context of organ development. Lung morphogenesis requires HH signalling which participates thereafter to the pulmonary homeostasis by regulating epithelial cell quiescence and repair. Since epithelial remodelling is a hallmark of...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Belgacemi, Randa, Luczka, Emilie, Ancel, Julien, Diabasana, Zania, Perotin, Jeanne-Marie, Germain, Adeline, Lalun, Nathalie, Birembaut, Philippe, Dubernard, Xavier, Mérol, Jean-Claude, Delepine, Gonzague, Polette, Myriam, Deslée, Gaëtan, Dormoy, Valérian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931110/
https://ncbi.nlm.nih.gov/pubmed/31877414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.11.033
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