Osteochondral Tissue Chip Derived From iPSCs: Modeling OA Pathologies and Testing Drugs

Osteoarthritis (OA) is a chronic disease mainly characterized by degenerative changes in cartilage, but other joint elements such as bone are also affected. To date, there are no disease-modifying OA drugs (DMOADs), owing in part to a deficiency of current models in simulating OA pathologies and eti...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Lin, Zixuan, Li, Zhong, Li, Eileen N., Li, Xinyu, Del Duke, Colin J., Shen, He, Hao, Tingjun, O'Donnell, Benjamen, Bunnell, Bruce A., Goodman, Stuart B., Alexander, Peter G., Tuan, Rocky S., Lin, Hang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930794/
https://ncbi.nlm.nih.gov/pubmed/31921815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00411
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