Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus Infection in an Open Fracture Animal Model

INTRODUCTION: Treatment of open fractures routinely involves multiple surgeries and delayed definitive fracture fixation because of concern for infection. If implants were made less susceptible to infection, a one-stage procedure with intramedullary nailing would be more feasible, which would reduce...

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Udgivet i:Biomed Res Int
Main Authors: Stavrakis, A. I., Zhu, S., Loftin, A. H., Weixian, X., Niska, J., Hegde, V., Segura, T., Bernthal, N. M.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930786/
https://ncbi.nlm.nih.gov/pubmed/31915682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1638508
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